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Molecular dissociation of the role of PSD-95 in regulating synaptic strength and LTD

PSD-95, a multi-domain protein enriched in the postsynaptic density, influences AMPA receptor (AMPAR) content at synapses and may play a critical role in LTD. Here we molecularly dissect the effects of PSD-95 on basal AMPAR-mediated synaptic responses and LTD using several complementary approaches....

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Detalhes bibliográficos
Main Authors: Xu, Weifeng, Schlüter, Oliver M., Steiner, Pascal, Czervionke, Brian L., Sabatini, Bernardo, Malenka, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147180/
https://ncbi.nlm.nih.gov/pubmed/18215622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.11.027
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