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Mammalian hyperplastic discs homolog EDD regulates microRNA-mediated gene silencing

MicroRNAs (miRNAs) regulate gene expression through translation repression and mRNA destabilization. However, the molecular mechanisms of miRNA silencing are still not well defined. Using a genetic screen in mouse embryonic stem (ES) cells, we identify mammalian hyperplastic discs protein EDD, a kno...

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Detalhes bibliográficos
Main Authors: Su, Hong, Meng, Shuxia, Lu, Yanyan, Trombly, Melanie I., Chen, Jian, Lin, Chengyi, Turk, Anita, Wang, Xiaozhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147021/
https://ncbi.nlm.nih.gov/pubmed/21726813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.013
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