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Mammalian hyperplastic discs homolog EDD regulates microRNA-mediated gene silencing
MicroRNAs (miRNAs) regulate gene expression through translation repression and mRNA destabilization. However, the molecular mechanisms of miRNA silencing are still not well defined. Using a genetic screen in mouse embryonic stem (ES) cells, we identify mammalian hyperplastic discs protein EDD, a kno...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147021/ https://ncbi.nlm.nih.gov/pubmed/21726813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.013 |
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