IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3

The lack of expression of the Suppressor of Cytokine Signalling-3 (SOCS3) or inactivation of the negative regulatory capacity of SOCS3 has been well documented in rheumatoid arthritis, viral hepatitis and cancer. The specific qualitative and quantitative consequences of SOCS3-deficiency on IL-6-medi...

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Bibliographic Details
Main Authors:	Croker, Ben A, Kiu, Hiu, Pellegrini, Marc, Toe, Jesse, Preston, Simon, Metcalf, Donald, O’Donnell, Joanne A, Cengia, Louise H, McArthur, Kate, Nicola, Nicos A, Alexander, Warren S, Roberts, Andrew W
Format:	Artigo
Language:	Inglês
Published:	2011
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3146962/ https://ncbi.nlm.nih.gov/pubmed/21519345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2011.29
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IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3

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