ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels in Non-Hispanic White Americans from the Look AHEAD Clinical Trial

BACKGROUND: Elevated triglyceride levels are a risk factor for cardiovascular disease. Angiopoietin-like protein 4 (Angptl4) is a metabolic factor that raises plasma triglyceride levels by inhibiting lipoprotein lipase (LPL). In non-diabetic individuals, the ANGPTL4 coding variant E40K has been asso...

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Main Authors: Smart-Halajko, Melissa C, Kelley-Hedgepeth, Alyson, Montefusco, Maria Claudia, Cooper, Jackie A, Kopin, Alan, McCaffrey, Jeanne M, Balasubramanyam, Ashok, Pownall, Henry J, Nathan, David M, Peter, Inga, Talmud, Philippa J, Huggins, Gordon S
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146919/
https://ncbi.nlm.nih.gov/pubmed/21714923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-89
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