Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage

BACKGROUND: Tenascin-C (TN-C) is an extracellular matrix glycoprotein that is involved in tissue injury and repair processes. We analyzed TN-C expression in normal and osteoarthritic (OA) human cartilage, and evaluated its capacity to induce inflammatory and catabolic mediators in chondrocytes in vi...

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Autors principals: Patel, Lisha, Sun, Weiyong, Glasson, Sonya S, Morris, Elisabeth A, Flannery, Carl R, Chockalingam, Priya S
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146914/
https://ncbi.nlm.nih.gov/pubmed/21762512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-12-164
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