An Integrative Genomics Approach Identifies Activation of Thioredoxin/Thioredoxin Reductase-1-Mediated Oxidative Stress Defense Pathway and Inhibition of Angiogenesis in Obese Nondiabetic Human Subjects

CONTEXT: Obesity is a complex disease that involves both genetic and environmental perturbations to gene networks in adipose tissue and is proposed as a trigger for metabolic sequelae. OBJECTIVE: We hypothesized that expression of adipose tissue transcripts in gene networks for adaptive response wou...

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Detalhes bibliográficos
Main Authors: Das, Swapan K., Sharma, Neeraj K., Hasstedt, Sandra J., Mondal, Ashis K., Ma, Lijun, Langberg, Kurt A., Elbein, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
JCEM Online: Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146788/
https://ncbi.nlm.nih.gov/pubmed/21593104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-0101
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