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Effects of diadenosine tetraphosphate on FGF9-induced chloride flux changes in achondroplastic chondrocytes
Achondroplasia, the most common type of dwarfism, is characterized by a mutation in the fibroblast growth factor receptor 3 (FGFR3). Achondroplasia is an orphan pathology with no pharmacological treatment so far. However, the possibility of using the dinucleotide diadenosine tetraphosphate (Ap(4)A)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146644/ https://ncbi.nlm.nih.gov/pubmed/21559786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-011-9234-y |
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