Widespread Deregulation of Phosphorylation-Based Signaling Pathways in Multiple Myeloma Cells: Opportunities for Therapeutic Intervention

Multiple myeloma (MM) is a neoplasm of plasma cell origin that is largely confined to the bone marrow (BM). Chromosomal translocations and other genetic events are known to contribute to deregulation of signaling pathways that lead to transformation of plasma cells and progression to malignancy. How...

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Bibliographic Details
Main Authors: Fuhler, Gwenny Manel, Diks, Sander Henricus, Peppelenbosch, Maikel Petrus, Kerr, William Garrow
Format: Artigo
Language:Inglês
Published: ScholarOne 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146594/
https://ncbi.nlm.nih.gov/pubmed/21541441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00013
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