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Widespread Deregulation of Phosphorylation-Based Signaling Pathways in Multiple Myeloma Cells: Opportunities for Therapeutic Intervention

Multiple myeloma (MM) is a neoplasm of plasma cell origin that is largely confined to the bone marrow (BM). Chromosomal translocations and other genetic events are known to contribute to deregulation of signaling pathways that lead to transformation of plasma cells and progression to malignancy. How...

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Detalhes bibliográficos
Main Authors: Fuhler, Gwenny Manel, Diks, Sander Henricus, Peppelenbosch, Maikel Petrus, Kerr, William Garrow
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146594/
https://ncbi.nlm.nih.gov/pubmed/21541441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00013
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