Multi-Modal Strategies for Overcoming Tumor Drug Resistance: Hypoxia, Warburg’s Effect, Stem Cells, and Multifunctional Nanotechnology

Inefficiency in systemic drug delivery and tumor residence as well microenvironmental selection pressures contribute to the development of multidrug resistance (MDR) in cancer. Characteristics of MDR include abnormal vasculature, regions of hypoxia, up-regulation of ABC-transporters, aerobic glycoly...

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Hlavní autoři: Milane, Lara, Ganesh, Shanthi, Shah, Shruti, Duan, Zhen-feng, Amiji, Mansoor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146561/
https://ncbi.nlm.nih.gov/pubmed/21497176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.03.032
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