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Impact of Protein Stability, Cellular Localization, and Abundance on Proteomic Detection of Tumor-Derived Proteins in Plasma

Tumor-derived, circulating proteins are potentially useful as biomarkers for detection of cancer, for monitoring of disease progression, regression and recurrence, and for assessment of therapeutic response. Here we interrogated how a protein's stability, cellular localization, and abundance af...

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Detalhes bibliográficos
Main Authors: Fang, Qiaojun, Kani, Kian, Faca, Vitor M., Zhang, Wenxuan, Zhang, Qing, Jain, Anjali, Hanash, Sam, Agus, David B., McIntosh, Martin W., Mallick, Parag
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146523/
https://ncbi.nlm.nih.gov/pubmed/21829587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023090
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