Mice Lacking TR4 Nuclear Receptor Develop Mitochondrial Myopathy with Deficiency in Complex I

The estimated incidence of mitochondrial diseases in humans is approximately 1:5000 to 1:10,000, whereas the molecular mechanisms for more than 50% of human mitochondrial disease cases still remain unclear. Here we report that mice lacking testicular nuclear receptor 4 (TR4(−/−)) suffered mitochondr...

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Hlavní autoři: Liu, Su, Lee, Yi-Fen, Chou, Samuel, Uno, Hideo, Li, Gonghui, Brookes, Paul, Massett, Michael P., Wu, Qiao, Chen, Lu-Min, Chang, Chawnshang
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146253/
https://ncbi.nlm.nih.gov/pubmed/21622535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0455
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