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Designing clinical trials to test disease-modifying agents—application to the treatment trials of Alzheimer's disease
BACKGROUND: Therapeutic trials of disease-modifying agents on Alzheimer’s disease (AD) require novel designs and analyses involving switch of treatments for at least a portion of subjects enrolled. Randomized start and randomized withdrawal designs are two examples of such designs. Crucial design pa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146242/ https://ncbi.nlm.nih.gov/pubmed/21335587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510392391 |
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