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Partial attenuation of cytotoxicity and apoptosis by SOD1 in ischemic renal epithelial cells

Reactive oxygen species (ROS) contribute significantly to apoptosis in renal ischemia-reperfusion (IR) injury, however the exact mechanisms are not well understood. We used novel lentiviral vectors to over-express superoxide dismutase 1 (SOD1) in proximal tubular epithelial (LLC-PK(1)) cells and det...

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Библиографические подробности
Главные авторы: Liang, Huan Ling, Arsenault, Jody, Mortensen, Jordan, Park, Frank, Johnson, Christopher P., Nilakantan, Vani
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146066/
https://ncbi.nlm.nih.gov/pubmed/19685188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-009-0393-z
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