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Contractile and electrophysiological properties of pulmonary artery smooth muscle are not altered in TASK-1 knockout mice

ABSTRACT: The acid-sensitive, two-pore domain K(+) channel, TASK-1, contributes to the background K(+) conductance and membrane potential (E(m)) of rat and human pulmonary artery smooth muscle cells (PASMCs), but its role in regulating tone remains elusive. This study aimed to clarify the role of TA...

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Detalhes bibliográficos
Main Authors: Manoury, Boris, Lamalle, Caroline, Oliveira, Roberta, Reid, Joy, Gurney, Alison M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145936/
https://ncbi.nlm.nih.gov/pubmed/21486782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.206748
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