KCNQ Modulators Reveal a Key Role for KCNQ Potassium Channels in Regulating the Tone of Rat Pulmonary Artery Smooth Muscle

Potassium channels are central to the regulation of pulmonary vascular tone. The smooth muscle cells of pulmonary artery display a background K(+) conductance with biophysical properties resembling those of KCNQ (K(V)7) potassium channels. Therefore, we investigated the expression and functional rol...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Joshi, Shreena, Sedivy, Vojtech, Hodyc, Daniel, Herget, Jan, Gurney, Alison M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Pharmacology and Experimental Therapeutics 2009
Pynciau:
Cardiovascular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684066/
https://ncbi.nlm.nih.gov/pubmed/19151245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.147785
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