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KCNQ Modulators Reveal a Key Role for KCNQ Potassium Channels in Regulating the Tone of Rat Pulmonary Artery Smooth Muscle

Potassium channels are central to the regulation of pulmonary vascular tone. The smooth muscle cells of pulmonary artery display a background K(+) conductance with biophysical properties resembling those of KCNQ (K(V)7) potassium channels. Therefore, we investigated the expression and functional rol...

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Autori principali: Joshi, Shreena, Sedivy, Vojtech, Hodyc, Daniel, Herget, Jan, Gurney, Alison M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Pharmacology and Experimental Therapeutics 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684066/
https://ncbi.nlm.nih.gov/pubmed/19151245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.147785
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