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CCN2/decorin interactions: a novel approach to combating fibrosis?

CCN2 (connective tissue growth factor, CTGF), a member of the CCN family is overexpressed in fibrotic disease and is essential for the development of experimental fibrosis. Drugs targeting CCN2 action may therefore prove to be useful anti-fibrotic approaches. CCN2 acts via integrins and heparan sulf...

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Detalhes bibliográficos
Autor principal: Leask, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145872/
https://ncbi.nlm.nih.gov/pubmed/21533889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-011-0134-2
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