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Maps of protein structure space reveal a fundamental relationship between protein structure and function
To study the protein structure–function relationship, we propose a method to efficiently create three-dimensional maps of structure space using a very large dataset of > 30,000 Structural Classification of Proteins (SCOP) domains. In our maps, each domain is represented by a point, and the distan...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145735/ https://ncbi.nlm.nih.gov/pubmed/21737750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102727108 |
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