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Maps of protein structure space reveal a fundamental relationship between protein structure and function

To study the protein structure–function relationship, we propose a method to efficiently create three-dimensional maps of structure space using a very large dataset of > 30,000 Structural Classification of Proteins (SCOP) domains. In our maps, each domain is represented by a point, and the distan...

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Detalhes bibliográficos
Main Authors: Osadchy, Margarita, Kolodny, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145735/
https://ncbi.nlm.nih.gov/pubmed/21737750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102727108
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