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Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1

Plasmodium falciparum malaria is a major cause of mortality and severe morbidity. Its virulence is related to the parasite's ability to evade host immunity through clonal antigenic variation and tissue-specific adhesion of infected erythrocytes (IEs). The P. falciparum erythrocyte membrane prot...

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Bibliografiske detaljer
Main Authors: Barfod, Lea, Dalgaard, Michael B., Pleman, Suzan T., Ofori, Michael F., Pleass, Richard J., Hviid, Lars
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145728/
https://ncbi.nlm.nih.gov/pubmed/21746929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103708108
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