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Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo

Cardiac hypertrophy is an adaptive growth process that occurs in response to stress stimulation or injury wherein multiple signal transduction pathways are induced, culminating in transcription factor activation and the reprogramming of gene expression. GATA4 is a critical transcription factor in th...

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Библиографические подробности
Главные авторы: van Berlo, Jop H., Elrod, John W., Aronow, Bruce J., Pu, William T., Molkentin, Jeffery D.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145698/
https://ncbi.nlm.nih.gov/pubmed/21746915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104499108
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