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The Transcription Factor GATA4 Is Activated by Extracellular Signal-Regulated Kinase 1- and 2-Mediated Phosphorylation of Serine 105 in Cardiomyocytes

The zinc finger-containing transcription factor GATA4 has been implicated as a critical regulator of multiple cardiac-expressed genes as well as a regulator of inducible gene expression in response to hypertrophic stimulation. Here we demonstrate that GATA4 is itself regulated by the mitogen-activat...

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Bibliographic Details
Main Authors: Liang, Qiangrong, Wiese, Russell J., Bueno, Orlando F., Dai, Yan-Shan, Markham, Bruce E., Molkentin, Jeffery D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC99918/
https://ncbi.nlm.nih.gov/pubmed/11585926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7460-7469.2001
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