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Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene

BACKGROUND: Benzo[a]pyrene (BaP) is a widespread environmental genotoxic carcinogen that damages DNA by forming adducts. This damage along with activation of the aryl hydrocarbon receptor (AHR) induces complex transcriptional responses in cells. To investigate whether human cells are more susceptibl...

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Autors principals: Hamouchene, Hamza, Arlt, Volker M, Giddings, Ian, Phillips, David H
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145607/
https://ncbi.nlm.nih.gov/pubmed/21714911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-333
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