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The role of the C8 proton of ATP in the regulation of phosphoryl transfer within kinases and synthetases
BACKGROUND: The kinome comprises functionally diverse enzymes, with the current classification indicating very little about the extent of conserved regulatory mechanisms associated with phosphoryl transfer. The apparent K(m )of the kinases ranges from less than 0.4 μM to in excess of 1000 μM for ATP...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145573/ https://ncbi.nlm.nih.gov/pubmed/21749731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-12-36 |
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