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Dynamic profiling of mRNA turnover reveals gene-specific and system-wide regulation of mRNA decay
RNA levels are determined by the rates of both transcription and decay, and a mechanistic understanding of the complex networks regulating gene expression requires methods that allow dynamic measurements of transcription and decay in living cells with minimal perturbation. Here, we describe a metabo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145553/ https://ncbi.nlm.nih.gov/pubmed/21680716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-01-0028 |
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