A phase 1 study of vinblastine in combination with carboplatin for children with low-grade gliomas: a Children's Oncology Group phase 1 consortium study

Both carboplatin and vinblastine have demonstrated single-agent activity in children with low-grade gliomas. A phase 1 trial evaluating 2 different schedules of these 2 agents in combination was performed: (1) Schedule A = carboplatin (140 mg/m(2)) weekly × 3 + vinblastine (4.5 or 3.5 mg/m(2)) weekl...

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Dettagli Bibliografici
Autori principali: Jakacki, Regina I., Bouffet, Eric, Adamson, Peter C., Pollack, Ian F., Ingle, Ashish M., Voss, Stephan D., Blaney, Susan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Clinical Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145477/
https://ncbi.nlm.nih.gov/pubmed/21764821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor090
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