Autophagy Protects Against Aminochrome-Induced Cell Death in Substantia Nigra-Derived Cell Line

Aminochrome, the precursor of neuromelanin, has been proposed to be involved in the neurodegeneration neuromelanin-containing dopaminergic neurons in Parkinson’s disease. We aimed to study the mechanism of aminochrome-dependent cell death in a cell line derived from rat substantia nigra. We found th...

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Dettagli Bibliografici
Autori principali: Paris, Irmgard, Muñoz, Patricia, Huenchuguala, Sandro, Couve, Eduardo, Sanders, Laurie H., Greenamyre, John Timothy, Caviedes, Pablo, Segura-Aguilar, Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Neurotoxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145404/
https://ncbi.nlm.nih.gov/pubmed/21427056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr060
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