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Mechanisms of Lipotoxicity in NAFLD and Clinical Implications

With the epidemic of childhood obesity, nonalcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease in pediatrics. NAFLD is strongly associated with insulin resistance, and increased level of serum free fatty acids (FFA)s. FFAs have direct hepatotoxicity throug...

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Detalhes bibliográficos
Main Authors: Ibrahim, Samar H., Kohli, Rohit, Gores, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145329/
https://ncbi.nlm.nih.gov/pubmed/21629127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0b013e31822578db
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