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Formation of Pancreatic Islets Involves Coordinated Expansion of Small Islets and Fission of Large Interconnected Islet-like Structures

The islets of Langerhans, micro-organs for maintaining glucose homeostasis, range in size from small clusters of <10 cells to large islets consisting of several thousand endocrine cells. Islet size distributions among various species are similar and independent of body size, suggesting an intrins...

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Main Authors: Jo, Junghyo, Kilimnik, German, Kim, Abraham, Guo, Charles, Periwal, Vipul, Hara, Manami
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145284/
https://ncbi.nlm.nih.gov/pubmed/21806924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.06.042
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