Proteomic Analysis Shows Synthetic Oleanane Triterpenoid Binds to mTOR

New multifunctional drugs that target multiple disease-relevant networks offer a novel approach to the prevention and treatment of many diseases. New synthetic oleanane triterpenoids (SO), such as CDDO (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) and its derivatives, are multifunctional compounds...

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Detalhes bibliográficos
Main Authors: Yore, Mark M., Kettenbach, Arminja N., Sporn, Michael B., Gerber, Scott A., Liby, Karen T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144948/
https://ncbi.nlm.nih.gov/pubmed/21818401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022862
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