Impaired Cognitive Function and Altered Hippocampal Synapse Morphology in Mice Lacking Lrrtm1, a Gene Associated with Schizophrenia

Recent genetic linkage analysis has shown that LRRTM1 (Leucine rich repeat transmembrane neuronal 1) is associated with schizophrenia. Here, we characterized Lrrtm1 knockout mice behaviorally and morphologically. Systematic behavioral analysis revealed reduced locomotor activity in the early dark ph...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Takashima, Noriko, Odaka, Yuri S., Sakoori, Kazuto, Akagi, Takumi, Hashikawa, Tsutomu, Morimura, Naoko, Yamada, Kazuyuki, Aruga, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144940/
https://ncbi.nlm.nih.gov/pubmed/21818371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022716
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