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Effect of dexamethasone and testosterone treatment on the regulation of insulin-degrading enzyme and cellular changes in ventral rat prostate after castration

Insulin-degrading enzyme (IDE) has been shown to enhance the binding of androgen and glucocorticoid receptors to DNA in the nuclear compartment. Glucocorticoids cause hyperglycaemia, peripheral resistance to insulin and compensatory hyperinsulinaemia. The aim of the present study was to investigate...

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Detalhes bibliográficos
Main Authors: César Vieira, Juliany S B, Saraiva, Karina L A, Barbosa, Maria C L, Porto, Regina C C, Cresto, Juan C, Peixoto, Christina A, Wanderley, Maria I, Udrisar, Daniel P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144516/
https://ncbi.nlm.nih.gov/pubmed/21507087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2011.00772.x
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