Comparative analysis of the ATRX promoter and 5' regulatory region reveals conserved regulatory elements which are linked to roles in neurodevelopment, alpha-globin regulation and testicular function

BACKGROUND: ATRX is a tightly-regulated multifunctional protein with crucial roles in mammalian development. Mutations in the ATRX gene cause ATR-X syndrome, an X-linked recessive developmental disorder resulting in severe mental retardation and mild alpha-thalassemia with facial, skeletal and genit...

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Autores principales: Tang, Paisu, Frankenberg, Stephen, Argentaro, Anthony, Graves, Jennifer M, Familari, Mary
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144453/
https://ncbi.nlm.nih.gov/pubmed/21676266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-200
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