HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore

Centromeres of higher eukaryotes are epigenetically marked by the centromere-specific CENP-A nucleosome. New CENP-A recruitment requires the CENP-A histone chaperone HJURP. In this paper, we show that a LacI (Lac repressor) fusion of HJURP drove the stable recruitment of CENP-A to a LacO (Lac operon...

Full description

Saved in:
Bibliographic Details
Main Authors: Barnhart, Meghan C., Kuich, P. Henning J. L., Stellfox, Madison E., Ward, Jared A., Bassett, Emily A., Black, Ben E., Foltz, Daniel R.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2011
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144403/
https://ncbi.nlm.nih.gov/pubmed/21768289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201012017
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items