β class II tubulin predominates in normal and tumor breast tissues

BACKGROUND: Antimitotic chemotherapeutic agents target tubulin, the major protein in mitotic spindles. Tubulin isotype composition is thought to be both diagnostic of tumor progression and a determinant of the cellular response to chemotherapy. This implies that there is a difference in isotype comp...

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Detalhes bibliográficos
Main Authors: Dozier, James H, Hiser, Laree, Davis, Jennifer A, Thomas, Nancy Stubbs, Tucci, Michelle A, Benghuzzi, Hamed A, Frankfurter, Anthony, Correia, John J, Lobert, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314434/
https://ncbi.nlm.nih.gov/pubmed/12927047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr631
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