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Shikonin Increases Glucose Uptake in Skeletal Muscle Cells and Improves Plasma Glucose Levels in Diabetic Goto-Kakizaki Rats

BACKGROUND: There is considerable interest in identifying compounds that can improve glucose homeostasis. Skeletal muscle, due to its large mass, is the principal organ for glucose disposal in the body and we have investigated here if shikonin, a naphthoquinone derived from the Chinese plant Lithosp...

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Détails bibliographiques
Auteurs principaux: Öberg, Anette I., Yassin, Kamal, Csikasz, Robert I., Dehvari, Nodi, Shabalina, Irina G., Hutchinson, Dana S., Wilcke, Mona, Östenson, Claes-Göran, Bengtsson, Tore
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144218/
https://ncbi.nlm.nih.gov/pubmed/21818330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022510
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