Downregulation of CD44 reduces doxorubicin resistance of CD44(+)CD24(−) breast cancer cells

BACKGROUND: Cells within breast cancer stem cell populations have been confirmed to have a CD44(+)CD24(−) phenotype. Strong expression of CD44 plays a critical role in numerous types of human cancers. CD44 is involved in cell differentiation, adhesion, and metastasis of cancer cells. METHODS: In thi...

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Bibliografske podrobnosti
Main Authors: Van Phuc, Pham, Nhan, Phan Lu Chinh, Nhung, Truong Hai, Tam, Nguyen Thanh, Hoang, Nguyen Minh, Tue, Vuong Gia, Thuy, Duong Thanh, Ngoc, Phan Kim
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2011
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143907/
https://ncbi.nlm.nih.gov/pubmed/21792314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S21431
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