A base-calling algorithm for Tm-shifted melting curve SNP assay

BACKGROUND: Tm-shifted melting curve SNP assays are a class of homogeneous, low-cost genotyping assays. Alleles manifest themselves as signal peaks in the neighbourhood of theoretical allele-specific melting temperatures. Base calling for these assays has mostly relied on unsupervised algorithm or h...

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Bibliografiske detaljer
Main Authors: Liang, Kung-Hao, Fen, Jun-Jeng, Chang, Hsien-Hsun, Wang, Hsei-Wei, Hwang, Yuchi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143900/
https://ncbi.nlm.nih.gov/pubmed/21884624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2043-9113-1-3
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