Phase I trial of vinflunine and pemetrexed in refractory solid tumors

BACKGROUND: Vinflunine is a novel vinca alkaloid with promising single agent clinical activity. Pemetrexed has at least additive activity with other vincas. A phase I trial was undertaken to assess the safety of vinflunine and pemetrexed in patients with refractory solid tumors. METHODS: A standard...

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Detalhes bibliográficos
Main Authors: Sanoff, Hanna K., Davies, Janine, Walko, Christine, Buie, Larry, Chiu, Wing-Keung, Ivanova, Anastasia, O’Neil, Bert, Stinchcombe, Thomas E., Keller, Kimberly, Dees, E. Claire
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143820/
https://ncbi.nlm.nih.gov/pubmed/19830387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-009-9344-3
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