Cu(II) Mediates Kinetically Distinct, Non-amyloidogenic Aggregation of Amyloid-β Peptides

Cu(II) ions are implicated in the pathogenesis of Alzheimer disease by influencing the aggregation of the amyloid-β (Aβ) peptide. Elucidating the underlying Cu(II)-induced Aβ aggregation is paramount for understanding the role of Cu(II) in the pathology of Alzheimer disease. The aim of this study wa...

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Bibliographische Detailangaben
Hauptverfasser: Pedersen, Jeppe T., Østergaard, Jesper, Rozlosnik, Noemi, Gammelgaard, Bente, Heegaard, Niels H. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Molecular Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143654/
https://ncbi.nlm.nih.gov/pubmed/21642429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.220863
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