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Assembly of a Filamin Four-domain Fragment and the Influence of Splicing Variant-1 on the Structure

Filamins are scaffold proteins that bind to various proteins, including the actin cytoskeleton, integrin adhesion receptors, and adaptor proteins such as migfilin. Alternative splicing of filamin, largely constructed from 24 Ig-like domains, is thought to have a role in regulating its interactions w...

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Detalhes bibliográficos
Main Authors: Pentikäinen, Ulla, Jiang, Pengju, Takala, Heikki, Ruskamo, Salla, Campbell, Iain D., Ylänne, Jari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143651/
https://ncbi.nlm.nih.gov/pubmed/21636571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.195958
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