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Assembly of a Filamin Four-domain Fragment and the Influence of Splicing Variant-1 on the Structure

Filamins are scaffold proteins that bind to various proteins, including the actin cytoskeleton, integrin adhesion receptors, and adaptor proteins such as migfilin. Alternative splicing of filamin, largely constructed from 24 Ig-like domains, is thought to have a role in regulating its interactions w...

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Auteurs principaux: Pentikäinen, Ulla, Jiang, Pengju, Takala, Heikki, Ruskamo, Salla, Campbell, Iain D., Ylänne, Jari
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143651/
https://ncbi.nlm.nih.gov/pubmed/21636571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.195958
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