Neuroprotection mediated by changes in the endothelial actin cytoskeleton

Cerebral blood flow is regulated by endothelium-derived nitric oxide (NO), and endothelial NO synthase–deficient (eNOS-deficient; eNOS(–/–)) mice develop larger cerebral infarctions following middle cerebral artery (MCA) occlusion. We report that disruption of Rho-mediated endothelial actin cytoskel...

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Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	Laufs, Ulrich, Endres, Matthias, Stagliano, Nancy, Amin-Hanjani, Sepideh, Chui, Dao-Shan, Yang, Shui-Xiang, Simoncini, Tommaso, Yamada, Masaru, Rabkin, Elena, Allen, Philip G., Huang, Paul L., Böhm, Michael, Schoen, Frederick J., Moskowitz, Michael A., Liao, James K.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 2000
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314365/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880044/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9639
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