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Effect of PAR2 in regulating TNF-α and NAD(P)H oxidase in coronary arterioles in type 2 diabetic mice

Protease-activated receptor-2 (PAR2) is expressed in endothelial cells and mediates endothelium-dependent vasodilation. We hypothesized that PAR2 regulates tumor necrosis factor-alpha (TNF-α)-induced coronary arteriolar dysfunction in type 2 diabetic (db/db) mice. To test this, coronary arterioles f...

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Detalhes bibliográficos
Main Authors: Park, Yoonjung, Yang, Jiyeon, Zhang, Hanrui, Chen, Xiaonai, Zhang, Cuihua
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143573/
https://ncbi.nlm.nih.gov/pubmed/20972877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-010-0129-9
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