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AGE/RAGE produces endothelial dysfunction in coronary arterioles in Type 2 diabetic mice

We hypothesized that impaired nitric oxide (NO)-dependent dilation (endothelial dysfunction) in Type 2 diabetes results, in part, from elevated production of superoxide (O(2)(•−)) induced by the interaction of advanced glycation end products (AGE)/receptor for AGE (RAGE) and TNF-α signaling. We asse...

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Autors principals: Gao, Xue, Zhang, Hanrui, Schmidt, Ann Marie, Zhang, Cuihua
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519223/
https://ncbi.nlm.nih.gov/pubmed/18539754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00464.2008
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