Heat shock protein 70 prevents secretagogue-induced cell injury in the pancreas by preventing intracellular trypsinogen activation

Rodents given a supramaximally stimulating dose of cholecystokinin or its analogue cerulein develop acute pancreatitis with acinar cell injury, pancreatic inflammation, and intrapancreatic digestive enzyme (i.e., trypsinogen) activation. Prior thermal stress is associated with heat shock protein 70...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	J Clin Invest
Prif Awduron:	Bhagat, Lakshmi, Singh, Vijay P., Hietaranta, Antti J., Agrawal, Sudhir, Steer, Michael L., Saluja, Ashok K.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Clinical Investigation 2000
Pynciau:	Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8706
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!