Heat shock protein 70 prevents secretagogue-induced cell injury in the pancreas by preventing intracellular trypsinogen activation

Rodents given a supramaximally stimulating dose of cholecystokinin or its analogue cerulein develop acute pancreatitis with acinar cell injury, pancreatic inflammation, and intrapancreatic digestive enzyme (i.e., trypsinogen) activation. Prior thermal stress is associated with heat shock protein 70...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Bhagat, Lakshmi, Singh, Vijay P., Hietaranta, Antti J., Agrawal, Sudhir, Steer, Michael L., Saluja, Ashok K.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 2000
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8706
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