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Albuterol-induced downregulation of Gsα accounts for pulmonary β(2)-adrenoceptor desensitization in vivo
The aim of the present study was to develop a chronic in vivo model of pulmonary β(2)-adrenoceptor desensitization and to elucidate the nature and molecular basis of this state. Subcutaneous infusion of rats with albuterol for 7 days compromised the ability of albuterol, given acutely, to protect ag...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC314356/ https://ncbi.nlm.nih.gov/pubmed/10880056 |
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