Potential mechanisms of human natural killer cell expansion in vivo during low-dose IL-2 therapy

The continuous, in vivo infusion of low-dose IL-2 selectively expands the absolute number of human natural killer (NK) cells after 4–6 weeks of therapy. The mechanism responsible for this expansion is unknown and was examined in this study. NK cells cultured at low concentrations of IL-2, comparable...

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Autores principales: Fehniger, Todd A., Bluman, Eric M., Porter, Michelle M., Mrózek, Ewa, Cooper, Megan A., VanDeusen, Jeffrey B., Frankel, Stanley R., Stock, Wendy, Caligiuri, Michael A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC314354/
https://ncbi.nlm.nih.gov/pubmed/10880055
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