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Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization
Vascular smooth muscle cells (VSMCs) at capacitance arteries of hypertensive individuals and animals undergo marked age- and blood pressure–dependent polyploidization and hypertrophy. We show here that VSMCs at capacitance arteries of rat models of hypertension display high levels of Akt1/PKB protei...
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| Опубликовано в: : | J Clin Invest |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11032861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8252 |
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