The therapeutic efficacy of S-1 against orthotopically implanted human pleural mesothelioma cells in severe combined immunodeficient mice

PURPOSE: Malignant pleural mesothelioma (MPM) is a highly lethal neoplasm. S-1 has been developed as a novel oral antineoplastic agent based on the modulation of 5-fluorouracil (5-FU) bioactivity. This study was conducted to investigate the preclinical therapeutic effect of S-1 on MPM. METHODS: We u...

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Bibliografiske detaljer
Main Authors: Van, Trung The, Hanibuchi, Masaki, Kakiuchi, Soji, Sato, Seidai, Kuramoto, Takuya, Goto, Hisatsugu, Mitsuhashi, Atsushi, Nishioka, Yasuhiko, Akiyama, Shin-ichi, Sone, Saburo
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2010
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143341/
https://ncbi.nlm.nih.gov/pubmed/21079960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1503-x
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